Figure 3.

Derivation of a three‐gene signature in a training cohort of ESCC patients. (A) LOXL2,CDH1, and FN1 are differentially expressed between 60 ESCC tumors and paired normal specimens in the training cohort (statistical significance assessed by the paired‐samples t test). (B) Kaplan–Meier curves of three genes (LOXL2,CDH1, and FN1) separately and the three‐gene signature for overall survival in the training cohort. Three‐gene signature prediction of high risk predicts poor survival in patients with ESCC.