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MiR‐375 directly targeted SLC7A11. (A) 3'UTR region of SLC7A11 mRNA is partially complementary to miR‐375. (B) The luciferase activities of HEK293T cells in different groups. (C) The expression of miR‐375 in transfected cells was measured by RT‐qPCR. (D–E) The mRNA expression and protein level of SLC7A11 was evaluated by RT‐qPCR and western blot respectively. ** P < 0.05. All data was presented as Mean ± SD from three independent experiments.
