. 2017 Jun 22;6(7):1817–1826. doi: 10.1002/cam4.1122

Table 1.

Frequency and relative frequency of neonatal cancers according to broad grouping and ICCC categories

ICCC Broad	Grouping	Gender (RF)		Race		Era		Total (RF)
ICCC Broad	Grouping	Male	Female	White	Non‐White	1973–1990	1991–2007	Total (RF)
Leukemias and Lymphomas (n = 93)	I Leukemias, myeloproliferative & myelodysplastic diseases:	46 (0.54)^a	39 (0.46)^a	69	16	13	72	85 (0.14)^b
	I(a) Lymphoid leukemias	12	8	15	5	3	17	20 (0.24)^a
	I(b) Acute myeloid leukemias	19	23	36	6	7	35	42 (0.49)^a
	I(c) Chronic myeloproliferative diseases	2	0	2	0	1	1	2 (0.02)^a
	I(d) Myelodysplastic syndrome and other myeloproliferative	1	0	1	0	0	1	1 (0.01)^a
	I(e) Unspecified and other specified leukemias	12	8	15	5	2	18	20 (0.24)^a
	II Lymphomas and reticuloendothelial neoplasms	4 (0.50)^a	4 (0.50)^a	7	1	1	7	8 (0.01)^b
	II(a) Hodgkin lymphomas	0	1	1	0	0	1	1 (0.13)^a
	II(b) Non‐Hodgkin lymphomas (except Burkitt lymphoma)	1	0	1	0	0	1	1 (0.13)^a
	II(d) Miscellaneous lymphoreticular neoplasms	3	3	5	1	1	5	6 (0.75)^a
CNS tumors (n = 68)	III CNS and misc intracranial and intraspinal neoplasms	35 (0.51)^a	33 (0.49)^a	58	10	22	46	68 (0.11)^b
	III(a) Ependymomas and choroid plexus tumor	4	2	4	2	2	4	6 (0.09)^a
	III(b) Astrocytomas	12	15	22	5	11	16	27 (0.40)^a
	III(c) Intracranial and intraspinal embryonal tumors	13	13	25	1	7	19	26 (0.38)^a
	III(d) Other gliomas	4	2	5	1	1	5	6 (0.09)^a
	III(f) Unspecified intracranial and intraspinal neoplasms	2	1	2	1	1	2	3 (0.04)^a
Other solid tumors (n = 451 + 3 patients were not classified by ICCC)	IV Neuroblastoma and other peripheral nervous cell tumors	103 (0.59)^a	71 (0.41)^a	143	31	58	116	174 (0.28)^b
	IV(a) Neuroblastoma and ganglioneuroblastoma	103	70	142	31	58	115	173 (0.99)^a
	IV(b) Other peripheral nervous cell tumors	0	1	1	0	0	1	1 (0.01)^a
	V Retinoblastoma	13 (0.48)^a	14 (0.52)^a	21	6	7	20	27 (0.04)^b
	VI(a) Nephroblastoma and other nonepithelial renal tumors	9 (0.56)^a	7 (0.44)^a	14	2	10	6	16 (0.03)^b
	VII(a) Hepatoblastoma	4 (0.57)^a	3 (0.43)^a	6	1	3	4	7 (0.01)^b
	IX Soft tissue and other extraosseous sarcomas	27 (0.53)^a	24 (0.47)^a	43	8	16	35	51 (0.08)^b
	IX(a) Rhabdomyosarcomas	11	8	17	2	8	11	19 (0.37)^a
	IX(b) Fibrosarcomas, peripheral nerve & other fibrous	9	13	17	5	7	15	22 (0.43)^a
	IX(d) Other specified soft tissue sarcomas	7	3	9	1	1	9	10 (0.20)^a
	X Germ cell & trophoblastic tumors & neoplasms of gonads	63 (0.38)^a	105 (0.63)^a	134	34	23	143	168 (0.27)^b
	X(a) Intracranial & intraspinal germ cell tumors	7	13	17	3	0	20	20 (0.12)^a
	X(b) Extracranial & extragonadal germ cell tumors	55	91	115	31	23	123	146 (0.87)^a
	X(c) Malignant gonadal germ cell tumors	1	0	1	0	0	1	1 (0.01)^a
	X(e) Other and unspecified malignant gonadal tumors	0	1	1	0	0	1	1 (0.01)^a
	XI Other malignant epithelial neoplasms and melanomas	1 (0.25)^a	3 (0.75)^a	2	2	2	2	4 (0.01)^b
	XI(d) Malignant melanomas	1	2	2	1	2	1	3 (0.75)^a
	XI(f) Other and unspecified carcinomas	0	1	0	1	0	1	1 (0.25)^a
	XII Other and unspecified malignant neoplasms	2 (0.50)^a	2 (0.50)^a	4	0	2	2	4 (0.01)^b
	XII(a) Other specified malignant tumors	1	1	2	0	0	2	2 (0.50)^a
	XII(b) Other unspecified malignant tumors	1	1	2	0	2	0	2 (0.50)^a
	Not classified by ICCC	3	0	1	2	1	2	3
	Grand Total	310 (0.50)^b	305 (0.50)	502	113	158	457

RF, relative frequency; RTh, radiation therapy; Surg, surgery.

Relative frequency was calculated as a fraction of the ICCC group.

Relative frequency was calculated as a fraction of total cases.