Table 1.
Characteristics of the study groups
| OO-IVLE | SMOF-IVLE | No-IVLE | HC | P value (4 groups) | P value (OO vs SMOF) | |
| Demographic, anthropometric and disease characteristics | ||||||
| N of subjects (M/F) | 15 (8/7) | 8 (3/5) | 8 (2/6) | 42 (19/23) | 0.4051 | |
| Age (yr) median (range) | 56 (19-78) | 44 (19-73) | 56 (29-64) | 46 (16-78) | 0.4051 | |
| BMI (kg/m2) median (range) | 22 (12-25) | 20 (17-23) | 21 (16-29) | 22 (17-26) | 0.1407 | |
| Cause of CIF n (%) | 0.0791 | |||||
| SBS | 9 (60) | 5 (62) | 8 (100) | |||
| Fistulas | - | 2 (25) | - | |||
| Dysmotility | 5 (33) | 1 (12) | - | |||
| Mucosal disease | 1 (7) | - | - | |||
| Primary disease n (%) | 0.0037 | |||||
| Mesenteric ischemia | 6 (40) | 1 (12) | 1 (12) | 0.0627 | ||
| CIPO | 5 (32) | 1 (12) | 4 (50) | |||
| Crohn’s disease | 1 (7) | 3 (36) | 3 (38) | |||
| Others | 3 (21) | 3 (36) | ||||
| Home parenteral nutrition schedule and oral feeding characteristics | ||||||
| HPN schedule: median (range) | ||||||
| Duration (mo) | 65 (2-261) | 29 (5-53) | 17 (6-278) | 0.2765 | - | |
| Current duration (mo) | 26 (2-96) | 7 (5-14) | 7 (2-19) | 0.0620 | 0.5682 | |
| Infusions (n/wk) | 7 (3.5-7) | 7 (2-7) | 7 (2-7) | 0.8028 | ||
| Lipids (n inf/wk) | 7 (3.5-7) | 7 (2-7) | - | - | 0.6946 | |
| (g/inf) | 48 (26-60) | 45 (28-56) | - | - | 0.8601 | |
| (g/kg of BW/inf) | 0.79 (0.38-1.10) | 0.86 (0.43-1.20) | - | - | 0.6260 | |
| (g/wk) | 210 (100-406) | 203 (180-350) | - | - | 0.8210 | |
| Glucose (g/inf) | 169 (84-350) | 198 (115-375) | 150 (36-265) | 0.3370 | - | |
| (g/kg of BW/inf) | 3.3 (1.4-5.5) | 3.8 (2.4-5.8) | 2.3 (0.9-5.0) | 0.5959 | - | |
| (g/wk) | 1014 (300-2450) | 1382 (473-2625) | 1050 (300-1855) | 0.4265 | - | |
| Amino acids (g/inf) | 50 (24-106) | 61 (50-100) | 29 (0-72) | 0.0553 | 0.2070 | |
| Energy (Kcal/inf) | 1400 (739-2104) | 1544 (837-2180) | 700 (144-1345) | 0.0117 | 0.4578 | |
| (Kcal/BEE × 100)1 | 99% (26%-149%) | 122% (59%-147%) | 54% (7%-116%) | 0.0568 | 0.4114 | |
| Oral feeding: median (range) | ||||||
| Intake (Kcal/d) | 1510 (0-2657) | 1071 (0-2827) | 1834 (930-2965) | 0.1114 | - | |
| Fat Absorption (% ingested) | 38 (0-88) | 27 (0-68) | 71 (21-95) | 0.1816 | - | |
1
Calculated by: [(Kcal/infusion × weekly frequency of infusions/7)/basal energy expenditure (BEE)] × 100. IVLE: Intravenous lipid emulsion; OO-IVLE group: Patients receiving a PN admixture containing Clinoleic 20%; SMOF-IVLE group: Patients receiving a PN admixture containing SMOF lipid ®20%; No-IVLE group: Patients receiving PN without IVLE; HC: Healthy controls; BMI: Body mass index; CIF: Chronic intestinal failure; BW: Body weight; SBS: Short bowel syndrome; CIPO: Chronic Intestinal Pseudo-obstruction; HPN: Home Parenteral Nutrition; Current duration: Duration of current parenteral nutrition admixture prescription.