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. 2017 Jul 7;23(25):4644–4653. doi: 10.3748/wjg.v23.i25.4644

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©The Author(s) 2017. Published by Baishideng Publishing Group Inc. All rights reserved.

This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial.

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Chronic acid reflux esophagitis and effects of banhasasim-tang treatment. A: Normal, normal rats; B: Control, untreated CARE modeled-rats; C: BHSST, BHSST-treated (1 g/kg body weight per day) CARE modeled-rats. Histology of the non-CARE esophagus revealed thin epithelium with few inflammatory cells. Whereas, CARE esophagus showed mucosal thickening with basal cell hyperplasia and marked inflammatory cell infiltration. These histological changes were improved by BHSST treatment. H&E staining; original magnification × 200. CARE: Chronic acid reflux esophagitis; BHSST: Banhasasim-tang.