Table 1.
Protocol 1 |
Protocol 2 |
|||
---|---|---|---|---|
CBH response | After apocynin | CBH response | After SOD | |
Control (C57Bl/6) | 84 ± 5 | 87 ± 6 | 82 ± 3 | 83 ± 5 |
apoE−/− × TGFβ1 | 61 ± 6† | 76 ± 3* | 59 ± 4† | 69 ± 5* |
apoE−/− | 75 ± 5 | 82 ± 4 | 73 ± 4 | 77 ± 5 |
TGFβ1 | 81 ± 6 | 87 ± 4 | 75 ± 4 | 80 ± 4 |
Values are means ± SE (n = 10/group) of carbachol (CBH) responses before and after apocynin (protocol 1) and before and after superoxide dismutase (SOD; protocol 2) in control (C57Bl/6) mice, apolipoprotein-deficient (apoE−/−) mice bearing transforming growth factor-β1 transgene (apoE−/− × TGFβ1), apoE−/− mice, and TGFβ1 mice.
P < 0.05 vs. control (C57Bl/6).
P < 0.05, before vs. after incubation.