Table 1.
Main subject characteristics
| Control | T2D | P Value | |
|---|---|---|---|
| Sex, men/women | 5/5 | 9/7 | |
| Age, yr | 46 ± 3 | 50 ± 2 | 0.334 |
| BMI, kg/m2 | 29 ± 2 | 31 ± 4 | 0.312 |
| Glucose, mg/dl | 95 ± 2 | 198 ± 22* | 0.001 |
| HbA1c, % | 5.3 ± 0.1 | 8.6 ± 0.5* | <0.001 |
| Insulin, μIU/ml | 7.6 ± 0.7 | 11 ± 2.3 | 0.293 |
| HOMA-IR | 1.8 ± 0.2 | 4.6 ± 0.7* | 0.013 |
| Triglycerides, mg/dl | 114 ± 20 | 184 ± 38 | 0.172 |
| Cardiovascular variables | |||
| Heart rate, beats/min | 63 ± 4 | 69 ± 3 | 0.212 |
| Systolic BP, mmHg | 122 ± 4 | 128 ± 4 | 0.313 |
| Diastolic BP, mmHg | 78 ± 2 | 81 ± 3 | 0.394 |
| Mean BP, mmHg | 91 ± 3 | 97 ± 3 | 0.258 |
| MSNA | N =10 | N =12 | |
| Burst frequency, bursts/min | 25 ± 4 | 31 ± 2 | 0.230 |
| Burst incidence, bursts/100 heartbeat | 39 ± 6 | 46 ± 4 | 0.361 |
| Total activity, AU/min | 1,241 ± 219 | 1,411 ± 139 | 0.520 |
Values are means ± SE.
T2D, Type 2 diabetes patient; BMI, body mass index; BP, blood pressure; MSNA, muscle sympathetic nerve activity.
*
P < 0.05 vs. control.