Table 4.
Hemodynamic variables of sham-operated rats and rats with left ventricle dysfunction
Groups | LVEDP (mmHg) | LVSP (mmHg) | +dP/dtmax (mmHg/s) | −dP/dtmax (mmHg/s) |
---|---|---|---|---|
Sed-Sham | 4.6 ± 1 | 120.1 ± 13.5 | 6113 ± 1389 | −4175 ± 932 |
RMT-Sham | 5.5 ± 1.6 | 122 ± 15.1 | 6644 ± 982 | −4247 ± 472 |
Sed-HF | 21.9 ± 5.2* | 93.1 ± 8.5* | 4071 ± 678† | −2602 ± 432† |
RMT-HF | 14.5 ± 6.7‡ | 113.4 ± 11 | 5237 ± 1630‡ | −2921 ± 852‡ |
Values are means ± SD; n = 8 for all groups. LVEDP, LV end-diastolic pressure; LVSP, LV systolic pressure; +dP/dtmax, LV maximum change in pressure over time; and −dP/dtmax, LV minimum change in pressure over time.
P < 0.01 compared with RMT-HF, RMT-Sham, and Sed-Sham;
P < 0.001 compared with RMT-Sham and Sed-Sham; and
P < 0.01 compared with RMT-Sham and Sed-Sham.