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Nitrite production from samples containing IMCD, vasa recta, and thin limb of Henle. All mice were on a HS7 diet. A: nitrite production was similar between VEETKO and flox control male mice. n = 4 animals/group, Student's t-test, P = 0.39. B: nitrite production was significantly reduced in samples from male CDET-1KO compared with their flox control. n = 4 flox and 3 CDET-1KO, Student's t-test, *P = 0.02.
