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Cartoon summary of alcohol-mediated regulation of ncRNAs. The blue and yellow boxes represent the “central dogma” concept of gene expression at the transcriptional or translational levels, and the potential mechanisms for ncRNA regulation are illustrated in red. Examples of lncRNA-mediated regulation of epigenetic factors (Neat2) and alcohol-induced changes in lncRNA methylation (H19) are shown. Alcohol may regulate both lncRNAs and miRNAs at the protein translational level.
