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. 2017 Jul 10;14:134. doi: 10.1186/s12974-017-0907-5

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© The Author(s). 2017

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 2 — Levels of a CXCL8, b CXCL9, and c CXCL10 in CSF of HSE (n = 14) and HSM (n = 20) patients compared to healthy controls (n = 33) and to serum (n = 8/group; control = 5). Data are presented as individual values with medians indicated by horizontal bars. CSF comparisons were performed using Kruskal-Wallis’ non-parametric test with Dunn’s post-test. White symbols are non-matched CSF or serum samples, which were excluded from analysis of paired CSF and serum (filled symbols), using Wilcoxon matched-pairs signed-rank test. Statistical analysis was performed using GraphPad Prism version 6 (GraphPad Software). Abbreviations: CSF cerebrospinal fluid, HSE herpes simplex encephalitis, HSM herpes simplex meningitis