Table 2.

Two year monthly cost estimates of patients treated for aortic valve stenosis

	Total costs of care		Costs of in-hospital care		Costs of outpatient care		Costs of nursing care
	Month 1	Month 2–24	Month 1	Month 2–24	Month 1	Month 2–24	Month 1–12	Month 13–24
Overall mean	3506.7	622.3	3439.1	452.6	16.12	35.13	104.7	174.0
	[2402.1,4611.4]	[473.6771.1]	[2338.1,4540.1]	[316.9588.3]	[8.377,23.85]	[32.40,37.86]	[55.65,153.8]	[89.25,258.7]
Male	3272.6	572.8	3311.0	441.0	17.60	37.33	67.99	113.7
	[1806.8,4738.4]	[333.4812.1]	[1902.4,4719.5]	[234.3647.6]	[8.822,26.39]	[33.17,41.50]	[10.04,125.9]	[21.24,206.2]
Female	3660.0	658.9	3512.9	461.9	14.74	33.53	133.5	215.5
	[2296.0,5024.0]	[476.9840.9]	[2201.9,4824.0]	[306.8617.0]	[7.418,22.07]	[30.00,37.05]	[62.05,204.9]	[100.1330.9]
TAVR	4247.5	711.0	3637.8	481.2	16.19	34.66	141.2	227.4
	[2472.9,6022.0]	[524.4897.6]	[2238.7,5036.9]	[314.3648.0]	[8.244,24.13]	[31.16,38.16]	[65.36,217.1]	[110.0,344.9]
AVR	2863.6	495.7	3182.2	411.3	16.19	35.78	56.03	94.47
	[1640.3,4086.8]	[264.9726.6]	[1854.2,4510.1]	[220.3602.2]	[7.963,24.42]	[31.53,40.04]	[6.171,105.9]	[13.84,175.1]
Patients aged 75–79 years	2779.6	509.9	3250.9	407.7	15.85	35.28	28.92	46.92
	[1453.1,4106.0]	[289.5730.3]	[1845.1,4656.7]	[223.5591.9]	[7.580,24.12]	[31.27,39.30]	[3.520,54.32]	[7.774,86.06]
Patients aged 80–84 years	4292.5	769.8	4297.0	560.3	15.47	35.77	114.5	173.3
	[2073.1,6511.9]	[461.5,1078.1]	[2221.7,6372.4]	[298.7821.8]	[7.464,23.47]	[30.68,40.86]	[29.22,199.8]	[58.11,288.5]
Patients aged ≥85 years	3840.7	629.6	3054.6	385.8	17.03	34.17	231.1	336.4
	[2313.3,5368.2]	[416.9842.3]	[1741.7,4367.4]	[212.7559.0]	[8.065,26.00]	[29.08,39.27]	[88.87,373.4]	[128.8544.0]
No death during follow-up	3013.4	500.7	2735.9	351.0	15.95	34.45	99.50	171.2
	[2013.5,4013.2]	[368.6632.8]	[1773.0,3698.8]	[235.9466.1]	[8.262,23.64]	[31.70,37.21]	[48.88,150.1]	[84.85,257.6]
Death during follow-up	9154.3	1703.2	8134.6	1285.9	15.93	41.49	137.8	232.8
	[3610.5,14,698.1]	[948.2,2458.2]	[4194.4,12,074.8]	[641.6,1930.2]	[5.420,26.43]	[31.56,51.42]	[−14.83,290.4]	[−9.125,474.7]
N	2250		2250		2250		2250

Separate two part models, with one (only time: month 1 vs. month 2–24, or month 1–12 vs month 13–24) or two (time and sex or procedure or ...) categorical covariates are conducted with a logistic regression analysis for part one and a generalized linear model with the log link and gamma distribution for the second part. Marginal means for the combined models are shown on the raw scale (€ per month). 95% confidence intervals in brackets. All estimates reflect cost estimates in Euro (basis year 2011) from a societal perspective