Table 1.
Demographic and clinical characteristics of patients with candidaemia and bacteraemia at the time of infection
| Variable | Candidaemia* (n = 73, 44%) | Bacteraemia** (n = 93, 56%) | P |
|---|---|---|---|
| Demographic variables | |||
| Age, years (median (IQR)) | 64 (52–76) | 67 (48–73) | 0.439 |
| Male gender | 43 (59) | 54 (58) | 0.913 |
| Clinical variables | |||
| Type of patient | 0.502 | ||
| Surgical | 28 (38) | 31 (33) | |
| Medical | 45 (62) | 62 (67) | |
| Previous abdominal surgery | 13 (18) | 16 (17) | 0.919 |
| Chronic renal failure | 19 (26) | 23 (25) | 0.849 |
| Diabetes mellitus | 14 (19) | 20 (22) | 0.712 |
| Charlson score (median (IQR)) | 3 (2-4) | 2 (2-5) | 0.546 |
| Presence of CVC | 60 (82) | 60 (65) | 0.012 |
| Haemodialysis | 7 (10) | 13 (14) | 0.389 |
| Receipt of albumin | 6 (8) | 17 (18) | 0.073 |
| Receipt of immunoglobulins | 0 (0) | 2 (2) | 0.504 |
| Corticosteroid therapy | 15 (21) | 17 (18) | 0.713 |
| Previous antibiotics | 64 (88) | 46 (49) | <0.001 |
| Previous antifungals | 12 (16) | 8 (9) | 0.124 |
| Candida colonization | 21 (29) | 23 (25) | 0.599 |
| Time from admission to candidaemia or bacteraemia, days (median (IQR)) | 21 (10–46) | 14 (8–29) | <0.001 |
Values are shown as n (%) unless otherwise indicated
* Candida albicans (n = 37), Candida parapsilosis (n = 23), Candida tropicalis (n = 7), Candida glabrata (n = 4), Candida guilliermondii (n = 1), Candida lusitaniae (n = 1)
** Klebsiella spp. (n = 23), Staphylococcus aureus (n = 12), Escherichia coli (n = 11), Pseudomonas aeruginosa (n = 11), coagulase-negative staphylococci (n = 8), Enterococcus spp. (n =5), Enterobacter spp. (n = 4), Proteus spp. (n = 4), Serratia spp. (n = 3), Acinetobacter spp. (n = 2), Streptococcus spp. (n = 2), Citrobacter spp. (n = 1), Providencia spp. (n = 1), Pseudomonas aeruginosa + Staphylococcus aureus (n = 1), Acinetobacter spp. + Pseudomonas aeruginosa (n = 1), Acinetobacter spp. + Staphylococcus aureus (n = 1), Enterococcus spp. + Klebsiella spp. (n = 1), Escherichia coli + Klebsiella spp. (n = 1), Escherichia coli + Pseudomonas aeruginosa (n = 1)
CVC central venous catheter, IQR interquartile range