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. 2017 Jul 10;19:81. doi: 10.1186/s13058-017-0873-y

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© The Author(s). 2017

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 2 — Age-related DNA methylation is enriched for regions of chromatin remodeling and transcriptional control. Cytosine-guanine dinucleotide (CpG) sites hypermethylated with age (a) and CpG sites hypomethylated with age (b) are highly enriched at the binding sites of transcription factors