Table 1.
Demographic and clinical characteristics of all new TB patients who had an unsuccessful TB treatment outcome, stratified by HIV status
| Variable | TB-HIV Co-infected n = 9991 n (%) |
95% confidence interval) | HIV negative n = 2089 n (%) |
95% confidence interval | HIV status not recorded n = 3192 n (%) |
95% confidence interval | Total n = 15,272 n (%) |
95% confidence interval |
|---|---|---|---|---|---|---|---|---|
| Sex | ||||||||
| Male | 5276 (52.8) | 51.8-53.8 | 1444 (69.1) | 67.1-71.1 | 1924 (60.3) | 58.6-62.0 | 8644 (56.6) | 55.8-57.4 |
| Female | 4715 (47.2) | 46.2-48.2 | 645 (30.9) | 28.9-32.6 | 1268 (39.7) | 38.2-41.4 | 6628 (43.4) | 42.6-44.2 |
| Age group | ||||||||
| 15-24 | 816 (8.2) | 7.6-8.7 | 318 (15.2) | 13.7-16.8 | 268 (8.4) | 7.4-9.4 | 1402 (9.2) | 8.7-9.6 |
| 25-34 | 3215 (32.2) | 31.3-33.1 | 342 (16.4) | 14.8-17.9 | 837 (26.2) | 24.7-27.7 | 4394 (28.8) | 28.1-29.5 |
| 35-44 | 3287 (32.9) | 32.0-33.8 | 322 (15.4) | 13.9-167.0 | 805 (25.2) | 23.7-26.7 | 4414 (28.9) | 28.2-29.6 |
| 45-54 | 1903 (19.0) | 18.3-19.8 | 395 (18.9) | 17.2-20.6 | 685 (21.5) | 20.0-22.9 | 2983 (19.5) | 18.9-20.2 |
| 55-64 | 643 (6.4) | 5.9-6.9 | 389 (18.6) | 16.9-20.3 | 362 (11.3) | 10.2-21.4 | 1394 (9.1) | 8.7-9.6 |
| ≥65 | 127 (1.3) | 323 (15.5) | 13.9-17.0 | 235 (7.4) | 6.5-8.3 | 685 (4.5) | 4.1-4.8 | |
| District | ||||||||
| A | 1786 (17.9) | 17.1-18.6 | 3 66 (17.5) | 15.9-19.2 | 448 (14.0) | 12.8-15.2 | 2600 (17.0) | 16.4-17.6 |
| B | 2449 (24.5) | 23.7-25.4 | 471 (22.5) | 20.8-24.3 | 482 (15.1) | 13.9-16.3 | 3402 (22.3) | 21.6-22.9 |
| C | 2649 (26.5) | 25.6-27.4 | 517 (24.8) | 22.8.9-26.6 | 1007 (31.6) | 29.9-33.1 | 4173 (27.3) | 26.728.0 |
| D | 2620 (26.2) | 25.4-27.1 | 540 (25.9) | 234.0-27.7 | 1104 (34.6) | 32.9-36.2 | 4264 (27.9) | 27.2-28.6 |
| E | 487 (4.9) | 4.4-5.3 | 195 (9.3) | 8.1-10.6 | 151 (4.7) | 4.0-5.5 | 833 (5.5) | 5.1-5.8 |
| Disease classification | ||||||||
| Both | 187 (1.9) | 1.6-2.1 | 26 (1.2) | 0.7-1.7 | 42 (1.3) | 0.9-1.7 | 255 (1.7) | 1.5-1.9 |
| Extra-pulmonary | 2135 (21.4) | 20.6-22.2 | 307 (14.7) | 13.2-16.2 | 832 (26.1) | 24.5-27.6 | 3274 (21.4) | 20.8-22.1 |
| Pulmonary | 7669 (76.7) | 75.9-77.6 | 1756 (84.1) | 82.5-85.6 | 2318 (72.6) | 71.0-74.2 | 11,743 (76.9) | 76.2-77.6 |
| Pre-treatment sputum smear resulta | ||||||||
| Sputum smear positive | 4346 (61.2) | 60.0-62.3 | 1083 (65.5) | 63.2-67.8 | 1196 (67.4) | 65.2-69.6 | 6625 (62.9) | 62.0-63.8 |
| Sputum smear negative | 2760 (38.8) | 37.7-40.0 | 571 (34.5) | 32.2-36.8 | 578 (32.6) | 30.3-34.8 | 3909 (37.1) | 36.2-38.0 |
| Treatment delayb | ||||||||
| 0-14 days | 4772 (83.0) | 82.1-84.1 | 1166 (85.3) | 83.4-87.2 | 1251 (85.5) | 83.7-87.3 | 7189 (83.8) | 83.1-84.6 |
| 15+ days | 974 (17.0) | 16.0-17.9 | 201 (14.7) | 12.8-16.5 | 212 (14.5) | 12.7-16.3 | 1387 (16.2) | 15.4-17.0 |
| On ART/CPT | ||||||||
| Neither on ART nor CPT only | 1292 (12.9) | 12.3-13.6 | NA | NA | NA | NA | 1292 (12.9) | 12.3-13.6 |
| On ART only | 367 (3.7) | 3.3-4.0 | NA | NA | NA | NA | 367 (3.7) | 3.3-4.0 |
| On CPT only | 4202 (42.1) | 41.1-43.0 | NA | NA | NA | NA | 4202 (42.1) | 41.1-43.0 |
| On both ART and CPT | 4130 (41.3) | 40.4-42.3 | NA | NA | NA | NA | 4130 (41.3) | 40.4-42.3 |
| CD4 count | ||||||||
| 1-200 | 4211 (75.9) | 74.7-77.0 | NA | NA | NA | NA | 4211 (75.9) | 74.7-77.0 |
| 201-350 | 839 (15.1) | 14.2-16.1 | NA | NA | NA | NA | 839 (15.1) | 14.2-16.1 |
| 351+ | 502 (9.0) | 8.2-9.8 | NA | NA | NA | NA | 502 (9.0) | 8.2-9.8 |
NA not applicable.
aHIV-positive n = 7106, HIV-negative n = 1654, HIV status unknown n = 1774
bHIV-positive n = 5746, HIV-negative n = 1367, HIV status unknown n = 1463