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. 2017 Jul 11;18:334. doi: 10.1186/s12859-017-1746-1

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© The Author(s) 2017

Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver(http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 1 — HLA-check pipeline: We start by augmenting the panel to test to get more SNP using an imputation phase with the 1000genomes data, then we compare those SNP alleles with their theoretical values for all possible HLA allele pairs