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. 2017 Jul 11;18:335. doi: 10.1186/s12859-017-1743-4

Table 2.

The contribution of each feature in the three methods: the backward deletion with either AIC or BIC and the L 1 regularization method

Selected methods Contribution
L1 & AIC & BIC Description L1 AIC BIC
1 x2 second largest intensity -7.2243 -20.211 -18.458
2 x4 average of (x1-x2) -21.93 -29.24 -26.646
3 x6 1/x3 -8.696 -11.815 -10.567
4 x7 x5 0.47013 1.2363 0.67037
5 x10 piecewise function of |x1-x2| 35.389 49.525 47.219
6 x11 14.579 27.974 26.622
7 x12 7.4602 28.731 26.943
8 x13 4.3013 36.89 34.142
9 x14 2.3397 106.05 97.787
10 x18 current cycle number -0.00054878 -0.00065167 -0.00061738
11 x28 A(AG) -5.3348 -12.956 -7.7384
12 x29 A(AT) -4.2171 -21.337 -7.2382
13 x39 C(AC) 14.771 18.74 14.901
14 x42 C(CA) -8.0916 -22.571 -11.925
15 x45 C(GA) -10.411 -57.22 -13.558
16 x53 G(AT) -3.3127 -24.44 -8.0976
17 x56 G(CT) -7.7223 -52.163 -11.508
18 x59 G(GT) -5.893 -77.08 -10.057
AIC & BIC Description L1 AIC BIC
1 x15 piecewise function of |x1-x2| 0 859.11 799.13
2 x16 0 19180 7549.6
L1 & AIC Description L1 AIC BIC
1 x5 standard error of (x1-x2) 121.95 -383.44 0
2 x8 log(x5) -2.8995 8.3866 0
3 x20 indicators of the first 7th cycles -3.0296 -30.195 0
4 x25 -5.4533 -12.32 0
5 x26 3.2316 126.13 0
6 x31 A(CG) 5.7108 -19.191 0
7 x32 A(CT) 1.864 -39.591 0
8 x33 A(GA) 9.9989 -22.428 0
9 x34 A(GC) 1.4679 -40.542 0
10 x35 A(GT) 11.712 -45.93 0
11 x36 A(TA) 5.7597 -45.042 0
12 x37 A(TC) 2.8418 -56.643 0
13 x43 C(CG) -5.6759 -42.894 0
14 x44 C(CT) -5.8779 -44.42 0
15 x46 C(GC) 7.3038 -28.805 0
16 x47 C(GT) 5.051 -42.573 0
17 x48 C(TA) 4.8103 -50.508 0
18 x50 C(TG) -4.0949 -85.841 0
19 x51 G(AC) 4.0089 -7.5339 0
20 x52 G(AG) 0.3575 -7.7936 0
21 x54 G(CA) 1.1807 -9.1835 0
22 x55 G(CG) -1.2149 -30.643 0
23 x57 G(GA) 13.802 -23.981 0
24 x58 G(GC) 1.9919 -47.805 0
25 x60 G(TA) 6.2969 -49.157 0
26 x61 G(TC) 1.9621 -75.049 0
27 x62 G(TG) 5.7278 -82.807 0
28 x64 T(AG) -1.6306 -11.911 0
29 x66 T(CA) 1.6158 -9.8488 0
30 x67 T(CG) -5.0538 -35.991 0
31 x68 T(CT) -0.72808 -41.646 0
32 x69 T(GA) 1.0712 -31.065 0
33 x70 T(GC) 5.0709 -35.774 0
34 x71 T(GT) 12.661 -42.749 0
35 x73 T(TC) -1.7016 -57.268 0
36 x74 T(TG) -6.1194 -72.443 0
AIC Description L1 AIC BIC
1 x38 A(TG) 0 -72.981 0
2 x40 C(AG) 0 -8.7049 0
3 x41 C(AT) 0 -19.167 0
4 x49 C(TC) 0 -63.57 0
5 x72 T(TA) 0 -48.82 0
L1 Description L1 AIC BIC
1 x1 largest intensity 1.0896 0 0
2 x3 average of x1 -6.0558 0 0
3 x9 piecewise function of |x1-x2| 13.791 0 0
4 x19 inverse distance -2.0626 0 0
5 x21 indicators of the first 7th cycles -1.5148 0 0
6 x24 -2.5247 0 0
7 x27 A(AC) -0.59405 0 0
8 x30 A(CA) 11.7 0 0
9 x65 T(AT) 15.749 0 0
None Description L1 AIC BIC
1 x17 piecewise function of |x1-x2| 0 0 0
2 x22 indicators of the first 7th cycles 0 0 0
3 x23 0 0 0
4 x63 T(AC) 0 0 0

The contribution is defined by the t-score, namely the coefficient divides by its standard error. All 74 features are classified into different groups by the method it is selected