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Antinociceptive effects of WFM in the tail-flick and capsaicin injection assay. (a) Antinociceptive effects in the tail-flick assay. WT mice were used in this assay. The time course of the tail-flick latencies was observed after WFM treatment (n = 8). (b, c) Effects of WFM in the capsaicin assay. WT mice were used in this assay (n = 8). (b) Number of licking and biting. (c) Time of licking and biting. Two-way ANOVA revealed significant drug effect. ∗p < 0.05, ∗∗p < 0.01, ∗∗∗p < 0.001.
