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. 2017 Jun 12;51(2):435–444. doi: 10.3892/ijo.2017.4038

Figure 2.

Figure 2

miR-449a suppresses proliferation and promotes apoptosis in LNcap and PC-3 cells. (A) The expression of miR-449a was detected in LNcap and PC-3 cells after miR-449a overexpression lentivirus or NC lentivirus infected by qRT-PCR. The result showed that miR-449a remarkably increased in LNcap and PC-3. ***P<0.001, unpaired two- tailed Student's t-test. (B) miR-449a overexpression delayed LNcap and PC-3 proliferation. **P<0.01, ***P<0.001, one-way ANOVA. (C) miR-449a promoted LNcap apoptosis. **P<0.01, unpaired two-tailed Student's t-test. (D) miR-449a promoted PC-3 cells apoptosis. ***P<0.001, unpaired two-tailed Student's t-test.