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PrLZ-shRNA inhibits proliferation and promotes apoptosis in LNcap and PC-3 cells. (A) PrLZ was detected by western blotting in LNcap and PC-3 cells after PrLZ shRNA lentivirus or NC lentivirus infection. ***P<0.001, unpaired two-tailed Student's t-test. (B) PrLZ shRNA suppressed LNcap and PC-3 proliferation. *P<0.05, **P<0.01, one-way ANOVA. (C and D) Downregulation of PrLZ promoted LNcap and PC-3 cell apoptosis. **P<0.01, ***P<0.001, unpaired two-tailed Student's t-test.
