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. 2017 Jun 8;40(2):389–399. doi: 10.3892/ijmm.2017.3014

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Copyright: © Wu et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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(-)-Epigallocatechin gallate (EGCG) pre-treatment enhances the protein expression of SIRT1 and manganese superoxide dismutase (MnSOD) in H9c2 cardiomyocytes subjected to hypoxia/reoxygenation (H/R)-injury. (A) Top panel: representative western blots of SIRT1 protein under the treatment of high glucose (HG), EGCG and/or SIRT1 siRNA. Bottom panel: quantification of western blot data from (A) top. (B) Top panel: representative western blots of MnSOD protein under the treatment of HG, EGCG and/or SIRT1 siRNA. Bottom panel: quantification of western blot data from (B) top. Values are the means ± SEM, n=6. ^*P<0.05 vs. HG + H/R group; ^#P<0.05 vs. HG + EGCG + H/R group; ^$P<0.05 vs. HG + EGCG + H/R + SI RT1 siRNA group.