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. 2017 Jun 9;40(2):337–346. doi: 10.3892/ijmm.2017.3016

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Copyright: © Hou et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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TPL attenuates anastomotic fibrosis and suppresses the synthesis of collagen. (A) Fibrosis score at anastomosis site in each group. (B) Results of western blot analysis for procollagen I and III in each group. The relative expression of procollagen I and III was statistically calculated compared to the β-actin level; (C) the ratios of the mean density of procollagen I at the anastomosis site in each group. (D) The ratios of the mean density of procollagen III at the anastomosis site in each group. The data are presented as the average ± SD of 6 independent experiments.^*P<0.05, significantly different from the WT group; ^#P<0.05, significantly different from the control group; ⁺P<0.05, significantly different from the ST-ICR group. TPL, triptolide; WT, wild-type; ST-ICR, saline-treated-ICRgroup; TT-ICR, triptolide-treated ICR group.