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. 2017 Jun 11;7(8):2339–2349. doi: 10.7150/thno.17555

Table 1.

IC50 of YD277 in 13 different cell lines, including 7 TNBC cell lines, 2 ERα-positive breast cancer cell lines, 1 colorectal cancer cell line, and 3 control cell lines.

Types Cell lines IC50 (μM)
ERα+ breast cancer MCF-7 1.5
T-47D 2
TNBC SUM149PT 2.5
MDA-MB-231 2
MDA-MB-453 6
MDA-MB-468 2
Hs578T 6
HCC1806 9
HCC1937 2
Normal MCF10A 8.5
HC11 20
NIH3T3 35
Colorectal cancer HCT116 10