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. 2017 Jul 11;16:136. doi: 10.1186/s12944-017-0529-z

Table 3.

Concentrations of EPA, DPA and DHA in the blood and tissues of Pten-knockout mice¹

		Group⁴, %
Tissue	Fatty acid	CON	L-ALA	H-ALA	EPA	n-3	n-6
blood	EPA	ND^2,a	4.05 ± 0.31^b	7.22 ± 0.28^c	10.1 ± 0.75^e	8.90 ± 0.37^d	ND^a
	DPA	ND^a	1.54 ± 0.04^c	2.14 ± 0.07^d	2.57 ± 0.18^e	1.20 ± 0.04^b	ND^a
	DHA	1.69 ± 0.11^b	5.50 ± 0.21^d	4.49 ± 0.29^c	6.19 ± 0.24^d	9.90 ± 0.52^e	0.78 ± 0.09^a
	Total³	1.69 ± 0.11^a	11.1 ± 0.46^b	13.9 ± 0.54^c	19.8 ± 0.53^d	20.0 ± 0.83^d	0.78 ± 0.09^a
liver	EPA	ND^a	4.90 ± 0.39^b	9.68 ± 0.46^c	8.29 ± 0.83^c	5.77 ± 0.52^b	ND^a
	DPA	0.11 ± 0.00^a	1.58 ± 0.11^b	2.18 ± 0.14^c	3.90 ± 0.45^d	1.84 ± 0.14^b,c	0.12 ± 0.02^a
	DHA	1.70 ± 0.17^a	10.9 ± 1.24^b	9.41 ± 0.59^b	14.0 ± 0.57^c	22.0 ± 0.77^d	1.98 ± 0.21^a
	Total	1.72 ± 0.18^a	18.8 ± 1.04^b	21.3 ± 0.80^c	26.2 ± 1.19^d	29.6 ± 0.80^e	2.07 ± 0.22^a
epididymal fat pad	EPA	ND^a	0.11 ± 0.01^a	0.20 ± 0.01^a	2.31 ± 0.15^c	1.49 ± 0.18^b	ND^a
	DPA	ND^a	0.17 ± 0.01^a	0.28 ± 0.01^b	0.86 ± 0.09^c	0.93 ± 0.07^c	ND^a
	DHA	ND^a	0.18 ± 0.02^a	0.16 ± 0.03^a	0.64 ± 0.07^b	2.76 ± 0.23^c	ND^a
	Total	ND^a	0.46 ± 0.03^a,b	0.64 ± 0.03^b	3.81 ± 0.28^c	5.17 ± 0.44^d	ND^a
prostate	EPA	ND^a	2.04 ± 0.26^b	3.82 ± 0.41^c	4.33 ± 0.96^c	3.43 ± 0.54^c	ND^a
	DPA	ND^a	2.30 ± 0.28^b	4.12 ± 0.30^c	4.14 ± 0.73^c	1.75 ± 0.13^b	ND^a
	DHA	2.18 ± 0.10^a	4.80 ± 0.54^b	5.14 ± 0.13^b	7.58 ± 0.63^c	9.93 ± 0.72^d	1.01 ± 0.13^a
	Total	2.18 ± 0.10^a	9.15 ± 0.87^b	13.1 ± 0.28^c	16.1 ± 2.18^d	15.1 ± 0.95^c,d	1.01 ± 0.13^a

¹Values are means ± SEMs (n = 6). Labeled means without a common letter differ, p < 0.05

²ND, not detected

³Total, the sum of EPA, DPA and DHA

⁴Data expressed as percentage of total fatty acids. L-ALA, low-ALA; H-ALA, high-ALA; CON, control