Table S1.
Summary of extracted data for mice coinfected with IAV and SP from previously published studies
Age (weeks) | Species | Virus
|
Bacteria
|
Cytokines | Reference | ||
---|---|---|---|---|---|---|---|
Strain | Dose (TCID50 mL−1) | Strain | Dose (CFU⋅mL−1) | ||||
8 | C57BL/6 | PR8 | 10 | Type 3 (ATCC 6303) | 104 | IL6, IL10, KC, TNFα, IFNγ | 1 |
8 | C57BL/6 | PR8 | 10 | Type 3 (ATCC 6303) | 2×105 | IL6, IL10, KC, TNFα | 2 |
6–12 | C57BL/6 | PR8 | 8.6×102 | Type 4 (ATCC 6304) | 107 | IL6, IL10, TNFα, IFNγ | 3 |
6 | BALB/c | PR8 | 1.8 | Type 2 (D39) | 102–105 | IL6, IL10, KC, TNFα | 4 |
6–8 | C57BL/6 without PAFR | PR8 | 102 | Type 2 (D39), type 3 (A66.1), type 4 (T4) | 102–104 | IL6, IL10, KC, TNFα | 5 |
8–10 | C57BL/6 | PR8 | 10 | Type 3 (ATCC 6303) | 2×104 | IL10, KC, TNFα, IFNγ | 6 |
7–10 | C57BL/6 | A/FM/1/47 (H1N1) | 1.4×105 | Type 3 (ATCC 6303) | 103 | KC, TNFα, IFNγ | 7 |
Abbreviations: IAV, influenza A virus; SP, Streptococcus pneumoniae; PAFR, platelet-activating factor receptor; KC, keratinocyte chemoattractant.