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The HIV-1 ASP transcript inhibits HIV-1 expression at the transcription level. ChIP assays measuring the presence of RNA Pol II at the HIV-1 promoter (Panel A), Nuc-1 (Panel B), and at the HIV-1 gag gene (Panel C) in Jurkat E4, JE4-LVX, and JE4-ASTmut before and after treatment with SAHA. Graphs report average and standard deviation calculated from three replicate samples.
