Table 1.
Control | REBOA | P-REBOA | ||||||||
---|---|---|---|---|---|---|---|---|---|---|
Mean | SEM | Mean | SEM | Mean | SEM | P | CxR | CxP | RxP | |
Baseline | ||||||||||
Aortic Flow | 2233.3 | 57.0 | 2331.7 | 112.3 | 2293.8 | 146.6 | 0.92 | |||
Proximal MAP | 79.6 | 1.9 | 75.1 | 1.5 | 77.8 | 2.2 | 0.28 | |||
Carotid Flow | 358.4 | 43.9 | 305.7 | 22.1 | 288.6 | 26.7 | 0.31 | |||
ICP | 0.8 | 0.1 | 0.1 | 0.3 | −0.1 | 0.8 | 0.46 | |||
CVP | 5.8 | 0.8 | 5.5 | 0.9 | 5.2 | 0.3 | 0.86 | |||
T30 Proximal MAP | 43.6 | 1.3 | 48.6 | 3.4 | 52.5 | 9.3 | 0.58 | |||
T30–90 Maximum | ||||||||||
Aortic Flow | 1241.3 | 228.4 | 0.0 | 12.1 | 338.8 | 51.2 | <0.01 | <0.01 | <0.01 | 0.22 |
Proximal MAP | 48.9 | 7.7 | 105.3 | 8.8 | 92.7 | 9.2 | <0.01 | <0.01 | <0.01 | 0.95 |
Carotid Flow | 170.3 | 29.4 | 673.1 | 57.9 | 464.2 | 53.0 | <0.01 | <0.01 | <0.01 | 0.02 |
Increase ICP | 3.1 | 0.8 | 5.7 | 2.3 | 4.6 | 1.0 | 0.49 | |||
CVP | 4.6 | 0.3 | 5.0 | 0.3 | 5.7 | 0.4 | 0.03 | 0.60 | 0.03 | 0.41 |
T30–90 Average | ||||||||||
Aortic Flow | 1122 | 210 | 0.2 | 14 | 319 | 17.4 | <0.01 | <0.01 | <0.01 | 0.20 |
Proximal MAP | 43.6 | 6.1 | 89.0 | 5.9 | 84.7 | 6.3 | <0.01 | <0.01 | <0.01 | 1.0 |
Carotid Flow | 169.9 | 27.3 | 529.3 | 39.3 | 408.5 | 38.3 | <0.01 | <0.01 | <0.01 | 0.08 |
Increase ICP | 1.9 | 0.7 | 3.4 | 0.8 | 2.3 | 0.5 | 0.26 | |||
CVP | 3.5 | 1.3 | 3.8 | 0.4 | 4.7 | 0.3 | 0.04 | 1.0 | 0.05 | 0.16 |
CPP | 27.4 | 5.5 | 67.6 | 6.3 | 66.2 | 5.7 | <0.01 | <0.01 | <0.01 | 1.0 |
T90–120 Maximum | ||||||||||
Aortic Flow | 3103 | 477.6 | 2288.5 | 324.7 | 2824.3 | 138.7 | 0.13 | |||
Proximal MAP | 97.3 | 6.7 | 79.2 | 1.6 | 81.2 | 1.7 | 0.01 | 0.02 | 0.04 | 1.0 |
Carotid Flow | 721.1 | 177.3 | 452.2 | 26.5 | 456.3 | 24.4 | 0.14 | |||
Increase in ICP | 12.8 | 1.2 | 5.1 | 0.6 | 9.4 | 1.1 | <0.01 | <0.01 | 0.08 | 0.02 |
CVP | 12.4 | 1.8 | 8.8 | 0.7 | 11.1 | 0.7 | 0.12 | |||
T100–360 Average | ||||||||||
Aortic Flow | 2540 | 173.1 | 1465 | 400.3 | 2407 | 127.4 | 0.02 | 0.04 | 1.0 | 0.07 |
Proximal MAP | 79.3 | 0.6 | 74.8 | 1.7 | 80.2 | 2.1 | 0.06 | |||
Carotid Flow | 477.3 | 126.6 | 422.7 | 21.1 | 362.5 | 31.6 | 0.58 | |||
ICP | 8.8 | 0.6 | 7.4 | 0.6 | 8.1 | 0.5 | 0.29 | |||
CVP | 6.0 | 0.2 | 5.2 | 1.8 | 6.4 | 0.4 | 0.10 | |||
CPP | 56.5 | 1.5 | 50.4 | 2.6 | 58.6 | 2.0 | 0.03 | 0.15 | 1.0 | 0.03 |
End ICP End CPP |
10.7 53.0 |
1.0 1.5 |
9.9 44.6 |
1.1 3.5 |
9.7 54.2 |
0.8 1.3 |
0.73 0.02 |
0.07 | 1.0 | 0.03 |
CxR: p-value for post-hoc analysis of Control by REBOA; CxP: p-value for post-hoc analysis of Control by PAO; RxP: p-value for post-hoc analysis of REBOA by PAO