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Islet Chemokines in Monogenic Rodent Models of Obesity and Diabetes.
| Animal Model (species) | Relevant Human Condition | Islet Chemokine Production | References |
|---|---|---|---|
| Akita (mouse) | ER stress/Insulin insufficiency | No* | Burke, Karlstad, & Collier, unpublished |
| db/db (mouse) | Obesity/T2D | Yes | (Burke et al. 2015a; Eguchi et al. 2012) |
| KKAy (mouse) | Obesity/T2D | Yes | (Eguchi et al. 2012) |
| ZDF (rat) | Obesity/T2D | Yes | (Jourdan, et al. 2013) |
male mice at 8 weeks of age.
