Table 3.
Multivariable Analysis of Patient Characteristics Associated With Postoperative Complications After Thyroid Cancer Surgery
| Clinical Factors | General Complications | Thyroid Surgery–Specific Complications |
|---|---|---|
| Age (y) | ||
| ≤65 (REF) | 1.00 | 1.00 |
| 65 | 2.61 (2.31–2.95) | 3.12 (2.85–3.42) |
| Sex | ||
| Male (REF) | 1.00 | 1.00 |
| Female | 0.90 (0.80–1.01) | 1.34 (1.22–1.47) |
| Race | ||
| White (REF) | 1.00 | 1.00 |
| Black | 1.42 (1.17–1.71) | 1.07 (0.90–1.26) |
| Other | 0.86 (0.72–1.02) | 1.03 (0.91–1.16) |
| Median household income | ||
| <$35,000 (REF) | 1.00 | 1.00 |
| $35,000–$59,999 | 0.83 (0.72–0.93) | 1.05 (0.94–1.16) |
| ≥$60,000 | 0.68 (0.52–0.87) | 1.03 (0.96–1.23) |
| Percent with no high school degree | ||
| <20% (REF) | 1.00 | 1.00 |
| 20%–29% | 1.04 (0.90–1.20) | 1.06 (0.95–1.19) |
| ≥30% | 1.09 (0.93–1.28) | 1.11 (0.98–1.26) |
| Rural-urban continuum | ||
| Metro (REF) | 1.00 | 1.00 |
| Other | 0.95 (0.80–1.12) | 1.09 (0.96–1.24) |
| Histology | ||
| Papillary (REF) | 1.00 | 1.00 |
| Follicular | 0.87 (0.71–1.07) | 0.75 (0.63–0.89) |
| Hürthle cell | 0.88 (0.69–1.12) | 0.71 (0.58–0.87) |
| Medullary | 1.00 (0.73–1.33) | 1.05 (0.83–1.31) |
| Stage | ||
| Localized (REF) | 1.00 | 1.00 |
| Regional | 1.18 (1.03–1.35) | 1.31 (1.19–1.45) |
| Distant | 2.83 (2.30–3.47) | 1.85 (1.54–2.21) |
| Unknown | 0.51 (0.08–1.68) | 1.34 (0.57–2.75) |
| Tumor size (cm) | ||
| ≤1 (REF) | 1.00 | 1.00 |
| 1.1–2 | 0.97 (0.83–1.13) | 1.00 (0.90–1.12) |
| 2.1–4 | 1.02 (0.87–1.20) | 1.06 (0.94–1.19) |
| 4 | 1.48 (1.24–1.76) | 1.23 (1.07–1.41) |
| Surgery | ||
| Lobectomy (REF) | 1.00 | 1.00 |
| Total thyroidectomy | 0.84 (0.73–0.96) | 1.59 (1.41–1.80) |
| Lymph nodes resected | ||
| No (REF) | 1.00 | 1.00 |
| Yes | 1.06 (0.93–1.20) | 1.43 (1.31–1.57) |
| Charlson/Deyo comorbidity score | ||
| 0 (REF) | 1.00 | 1.00 |
| 1 | 2.40 (1.66–3.49) | 1.88 (1.53–2.31) |
| ≥2 | 7.05 (5.33–9.56) | 3.62 (3.11–4.25) |
Values are OR (95% CI).
Abbreviation: REF, reference.