Figure 4.

Levels of progesterone (a, b) and estradiol (a) in spent culture media 1 day after transfection of hLGCs with the indicated oligonucleotides (n = 6 experiments). (c) Transcript levels of different genes involved in cholesterol and steroid production, quantified by qPCR in hLGC samples collected 1 day after transfection with the indicated oligonucleotides (n = 3 experiments). Mean (±SE) values are shown and were normalized to values on the day of transfection (day 0). Group means with different letters (a, b, c) are significantly different (P < 0.05).