. 2017 Apr 28;102(7):2533–2542. doi: 10.1210/jc.2017-00224

Table 5.

Correlations Between Thyroid Hormone Levels and Dietary Intake and Physical Activity Measures in L-T4–Treated Subjects

Measure^a	fT4 (n = 139)		fT3 (n = 139)		TSH (n = 140)
Measure^a	Coefficient^b	P Value^c	Coefficient	P Value	Coefficient	P Value
Daily energy intake, kcal/kg/d	2.51	0.30	−0.02	0.90	0.27	0.64
% CHO intake	−0.95	0.61	−0.01	0.94	0.48	0.30
% Fat intake	3.29	0.14	0.21	0.14	−1.13	0.03^d
% Protein intake	−0.88	0.44	−0.07	0.34	0.57	0.04^d
Total daily PAEE, kcal/d	57.02	0.47	9.49	0.06	−36.91	0.049^d
Daily PAEE per kg LBM	2.08	0.19	0.17	0.10	−0.67	0.08
Daily PAEE—light, kcal/d	−9.69	0.56	4.00	0.0002^e	−4.55	0.26
Daily PAEE—moderate/vigorous, kcal/d	68.36	0.32	5.57	0.22	−32.18	0.05
Daily time spent in sedentary activities, min	−31.83	0.35	−2.28	0.31	9.17	0.27
Daily time spent in light activities, min	−7.49	0.66	3.08	0.01^f	−3.83	0.36
Daily time spent in moderate/vigorous activities, min	7.44	0.76	1.12	0.48	−9.29	0.11
% Daily time spent in sedentary activities	−1.86	0.58	−0.35	0.10	1.24	0.13
% Daily time spent in light activities	0.12	0.95	0.29	0.01^f	−0.33	0.43
% Daily time spent in moderate/vigorous activities	1.50	0.49	0.10	0.47	−0.93	0.07

Abbreviation: CHO, carbohydrate.

^{^a}

Diet measures were available in all subjects. Physical activity measures were available in all but two subjects. Correlations were analyzed by repeated measures methodology using separate models for each hormone.

^{^b}

Positive coefficients indicate that the measure increased with increasing hormone levels; negative coefficients indicate that the measure decreased with increasing hormone levels. The magnitude of the coefficient indicates the estimated change in the measure with a one-unit increase in fT4 or TSH or a 10-unit increase in fT3.

^{^c}

P values were adjusted for age, estrogen status, L-T4 time, L-T4 dose time, and L-T4 dose (μg/kg). Significant coefficients are shown in bold with corresponding P values unadjusted for multiple comparisons.

^{^d}

P value is not significant at the 0.05 level both when applying multiple testing adjustments using a Bonferroni correction and when using the false discovery rate.

^{^e}

P value is still significant at the 0.05 level both when applying multiple testing adjustments using a Bonferroni correction and when using the false discovery rate.

^{^f}

P value is still significant at the 0.05 level when applying multiple testing adjustment using the false discovery rate.