Table 2. CSF biomarkers predict cognitive performance at baseline.

Numbers listed are the linear mixed model coefficient ± standard error. Each unit indicates a one standard deviation change from the mean. A negative value indicates that a higher CSF biomarker measure is associated with worse performance.

	Aβ42	Tau	pTau	Tau/Aβ42	pTau/Aβ42
Logical memory	0.154 ± 0.07*	−0.084 ± 0.06	−0.093 ± 0.06	−0.232 ± 0.07***	−0.229 ± 0.07***
FCSRT-free	0.028 ± 0.06	−0.169 ± 0.06*	−0.116 ± 0.06	−0.185 ± 0.06**	−0.130 ± 0.06*
Global cognition	0.062 ± 0.03*	−0.019 ± 0.03	−0.020 ± 0.03	−0.086 ± 0.03**	−0.077 ± 0.03*
Sequencing	0.232 ± 0.07***	−0.082 ± 0.07	0.117 ± 0.07	−0.162 ± 0.07*	−0.029 ± 0.07
MMSE	0.089 ± 0.07	−0.040 ± 0.06	0.015 ± 0.06	−0.132 ± 0.06*	−0.062 ± 0.07
Associate learning	0.009 ± 0.06	0.034 ± 0.06	0.047 ± 0.06	−0.036 ± 0.06	−0.003 ± 0.06
Trails B	0.190 ± 0.06***	0.117 ± 0.05*	0.098 ± 0.05	−0.035 ± 0.06	−0.046 ± 0.06
Trails A	−0.008 ± 0.06	0.035 ± 0.06	−0.011 ± 0.06	0.033 ± 0.06	0.010 ± 0.06
Category	−0.028 ± 0.07	0.000 ± 0.07	−0.082 ± 0.06	−0.013 ± 0.07	−0.057 ± 0.07

^*p<0.05 (yellow),

^**p<0.01 (orange),

^***p<0.001 (red)