Table 4.
Changes in organ weight: Body weight ratios with prenatal treatment and postnatal overfeeding. Groups with different alphabetic notations are different from each other.
| Parameter (Ratios) | Control-NF | BPA-NF | Control-OF | BPA-OF |
Treatment effect |
Diet effect |
Prenatal Treatment x Diet interaction |
|---|---|---|---|---|---|---|---|
| Heart weight:BW (X10−3) | 3.59±0.07 | 3.18±0.25 | 3.53±0.0.09 | 3.33±0.14 | NS | NS | NS |
| Liver weight:BW (X10−3) | 7.82±0.32 | 8.11±0.36 | 8.11±0.19 | 7.7±0.16 | NS | NS | NS |
| Lung weight:BW (X10−3) | 8.85±0.46 a |
6.26±0.19 b |
7.78±0.34 a,b |
7.09±0.79 a,b |
Yes p=0.003 |
NS | NS |
|
Spleen weight:BW (X10−3) |
7.82±0.32 | 8.11±0.36 | 8.11±0.19 | 7.7±0.16 | NS | NS | NS |
|
Right adrenal weight:BW (X10−2g/kg) |
2.61±0.26 a |
2.06±0.09 a,b |
2.31±0.19 a,b |
1.99±0.06 b |
Yes p=0.013 |
NS | NS |
|
Left adrenal weight:BW (X10−2 g/kg) |
2.69±0.27 a |
2.18±0.12 a,b |
2.28±0.15 a,b |
2.04±0.08 b |
Yes p=0.029 |
NS | NS |
|
Right kidney weight:BW (g/kg) |
0.89±0.02 a |
0.66±0.02 b |
0.88±0.03 c |
0.74±0.02 c |
Yes p<0.001 |
NS | NS |
|
Left Kidney weight:BW (g/kg) |
0.88±0.02 a |
0.65±0.02 b |
0.85±0.019 c |
0.74±0.01 d |
Yes p<0.0001 |
NS | Yes p=0.0126 |
“a,b” indicates no change from “a” and “b”. If there are no notations, it indicates that there are no significant changes between groups. NS indicates no significant differences.