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. Author manuscript; available in PMC: 2017 Jul 11.
Published in final edited form as: Adv Pharmacol. 2014 Aug 22;71:203–243. doi: 10.1016/bs.apha.2014.06.002

Figure 6.

Figure 6

Overall survival (OS) in patients newly diagnosed with primary CNS lymphoma according to risk groups. OS is from the date of first intraarterial in conjunction with blood-brain barrier disruption treatment stratified by age and Karnofsky Performance Score (KPS). Low risk, age younger than 60 years with KPS ≥70 (47 patients); moderate risk, age older than 60 years with any KPS or age younger than 50 years with KPS <70 (89 patients); high risk, age 50 to less than 60 years with KPS <70 (13 patients) (P>0.0001). In low-risk patients, median OS was approximately 14 years, with a survival plateau after approximately 8 years. Symbols on lines indicate censored observations. Reprinted with permission from Angelov et al. (2009), © 2009 American Society of Clinical Oncology.