Table 3.
Multivariable Linear Regression Models (Dependent Variable: Calculated/Prescribed Daily Insulin Dose) in Insulin-Treated Type 2 Diabetes Patients in Primary Care.
| Variable | Short-acting insulins | Long-acting insulins | Premixed insulins |
|---|---|---|---|
| Age (per year) | 0.11 (<0.01) | 0.04 (<0.01) | 0.10 (<0.01) |
| Male sex | 1.40 (0.07) | −0.19 (0.55) | −0.31 (0.67) |
| Private health insurance (yes/no) | 1.18 (0.58) | −0.41 (0.56) | 0.23 (0.90) |
| Diabetologist care (yes/no) | −2.92 (<0.01) | −1.02 (0.02) | −3.65 (<0.01) |
| HbA1c (%) | −0.77 (0.01) | 0.47 (<0.01) | 0.56 (0.03) |
| Obesity (BMI ≥ 30 kg/m2) (yes/no) | 1.38 (0.39) | −0.62 (0.35) | 1.96 (0.24) |
| Hypertension (yes/no) | 1.20 (0.25) | 0.01 (<0.01) | −0.79 (0.40) |
| Hyperlipidemia (yes/no) | −0.17 (0.82) | 0.31 (0.31) | −0.60 (0.41) |
| Macrovascular complications (yes/no) | 0.37 (0.64) | 0.73 (0.72) | −0.91 (0.23) |
| Microvascular complications (yes/no) | −0.75 (0.34) | 0.56 (0.56) | 0.47 (0.52) |
Data are ß-regression coefficients (P values). R2: short-acting insulin model: .004, long-acting insulin model: .001; premixed insulin model: .004. Macrovascular complications: myocardial infarction, stroke, coronary heart disease, or peripheral vascular disease. Microvascular complications: peripheral neuropathy, retinopathy, or nephropathy.