Table 1.

Baseline characteristics and status of GERD testing of subjects assessed by BALF MP

Testing for reflux	8 Patients with reflux on barium swallow
	24 h ambulatory pH monitoring: 26 patients tested, median DeMeester score 11.2, range 0.8–58
Antireflux therapy	26 Patients (90%), PPI 25 patients, H2 blocker 1 patient
Patient age	Mean 55, range 16–67
Patient gender	13 Female, 16 male
Fundoplication	3 Patients treated with gastrofundoplication between samples, 2 patients with pretransplant gastrofundoplication
Esophageal function	Normal 10 patients; decreased peristalsis 10 patients; hypertensive lower esophageal sphincter 7 patients; untested 2 patients
Patients at lowest risk for aspiration	DeMeester <14, no reflux on barium esophagram, normal esophageal motility: 5 patients (17%)

BALF MP, bronchoalveolar lavage fluid metabolomic profiling; COPD, chronic obstructive pulmonary disease; GERD, gastroesophageal reflux disease; IPF, idiopathic pulmonary fibrosis; PPI, proton pump inhibitor.

Disease indication for lung transplant: COPD 12, IPF 13, sarcoid 2, obliterative bronchiolitis 1, cystic fibrosis 1.