Figure 1. Astragalus polysaccharides (APS) ameliorated ultrastructural abnormalities in diabetic hearts. Heart samples were evaluated using an electron microscope to define cardiac mitochondrial structural changes. Representative ultrastructural profiles of ventricular cardiac myocytes using a transmission electron microscope (original magnification: ×5,700 in A-D, ×23,300 in E and F). A, Diabetic mice; B, diabetic mice with APS treatment; C, superoxide dismutase knockout (SOD2+/-) mice; D, SOD2+/- mice with APS treatment; E, diabetic SOD2+/- mice; F, diabetic SOD2+/- mice with APS treatment.