Figure 2. Astragalus polysaccharides (APS) affected the apoptosis, necrosis and proliferation of the myocardium in diabetes. A, Myocyte apoptosis in the left ventricle (detected by hairpin 1); B, myocyte necrosis in the left ventricle (detected by hairpin 1 and hairpin 2); C, proliferation of myocytes in the left ventricle. Data are reported as means±SE. ^!P<0.05 vs diabetic mice (DM); ^#P<0.05 vs SOD2+/-mice; ^?P<0.05 vs diabetic SOD2+/- mice; *P<0.05 vs C57BJ/6J control mice (one-way ANOVA). D, Immunohistochemistry microphotographs showing the apoptosis, necrosis and proliferation of cardiomyocytes derived from the left ventricle (white arrows: apoptosis; white asterisk: necrosis; #: proliferation). LV: left ventricle.