. Author manuscript; available in PMC: 2018 Jun 1.

Published in final edited form as: Eur J Obstet Gynecol Reprod Biol. 2017 Apr 13;213:107–115. doi: 10.1016/j.ejogrb.2017.04.025

Table 4.

Summary of three studies assessing reproductive outcome with IVF or ICSI after polyp removal or expectant management.

Study	Design	Patients	Intervention	Pregnancy Rate		Spontaneous Miscarriage Rate		Ongoing Pregnancy Rate
Study	Design	Patients	Intervention	S	C	S	C	S	C
Lass et al.	RCC	70 subfertile women age 35.4±3.6 (S) 35.4±3.8 (C) EP <20 mm	HSC polypectomy + IVF + FET vs. IVF	7/21	11/49	1/7	3/11	28.6% 6/21	16.3% 8/49
Isikoglu et al.	RCC	55 subfertile women age 28-34 (S) 29-38 (C) majority of EP <15 mm	HSC polypectomy + ICSI vs. ICSI	18/40	8/15	0/18	1/8	45.0% 18/40	46.7% 7/15
Ghaffari et al.	CS	86 subfertile women age 33.9±3.9 (S) 32.5±4.4 (C) matched by polyp size, EP <20mm	HSC polypectomy + ICSI vs. ICSI	15/43	14/43	2/15	2/14	30.2% 13/43	27.9% 12/43
Average				40/104	33/107	3/40	6/33	35.6% 37/104	25.2% 27/107

S=Study Group, C=Control Group

RCC=retrospective case control

CS=cross-sectional

EP=endometrial polyp

HSC=hysteroscopic

IVF=in vitro fertilization

FET=frozen embryo transfer

ICSI=intracytoplasmic sperm injection