Table 5.

Calculated overall cost per ongoing pregnancy after hysteroscopic polypectomy (office or operative) versus expectant management based on the pregnancy rates from three IVF/ICSI studies.

Office Procedure	IVF/ICSI
	Hysteroscopic Polypectomy				Expectant Management
	Study	Ongoing Pregnancy Rate	Treatment Cost	Cost per Ongoing Pregnancy	Ongoing Pregnancy Rate	Treatment Cost	Cost per Ongoing Pregnancy	Cost Savings
	Lass et al.	28.6%	€16,1831	€56,584	16.3%	€15,4502	€94,788	€38,204
			$18,183	$63,577		$17,360	$106,503	$42,926
	Isikoglu et al.	45.0%	€16,1831	€35,962	46.7%	€15,4502	€33,084	−€2,878
			$18,183	$40,407		$17,360	$37,173	−$3,234
	Ghaffari et al.	30.2%	€16,1831	€53,586	27.9%	€15,4502	€55,378	€1,792
			$18,183	$60,209		$17,360	$62,222	$2,013
	Average	35.6%	€16,1831	€45,458	25.2%	€15,4502	€61,311	€15,854
			$18,183	$51,076		$17,360	$68,889	$17,813
Operative Procedure	Hysteroscopic Polypectomy				Expectant Management
	Study	Ongoing Pregnancy Rate	Treatment Cost	Cost per Ongoing Pregnancy	Ongoing Pregnancy Rate	Treatment Cost	Cost per Ongoing Pregnancy	Cost Savings
	Lass et al.	28.6%	€19,4623	€68,048	16.3%	€15,4502	€94,788	€26,740
			$21,867	$76,458		$17,360	$106,503	$30,045
	Isikoglu et al.	45.0%	€19,4623	€43,248	46.7%	€15,4502	€33,084	−€10,164
			$21,867	$48,593		$17,360	$37,173	−$11,420
	Ghaffari et al.	30.2%	€19,4623	€64,442	27.9%	€15,4502	€55,378	−€9,064
			$21,867	$72,407		$17,360	$62,222	−$10,185
	Average	35.6%	€19,4623	€54,667	25.2%	€15,4502	€61,311	€6,644
			$21,867	$61,424		$17,360	$68,889	$7,465

IVF=in vitro fertilization

ICSI=intracytoplasmic sperm injection

¹Calculated cost of IVF/ICSI with office hysteroscopic polypectomy

²Calculated cost of IVF/ICSI

³Calculated cost of IVF/ICSI with operative hysteroscopic polypectomy

€=Converted 2016 Euros; $=2016 US Dollars

Cost savings is expectant management cost minus polypectomy cost and favors polypectomy