Table 1.
Population characteristics and rate and odds of MT-sDNA screening (compared to colonoscopy) by age, sex, race, and prior CRC screening
| N, (%) | Colonoscopy N (%) |
MT-sDNA N (%) |
Odds of MT-sDNA OR (95% CI)2 |
|
|---|---|---|---|---|
| Total | N=27,147 | 2,193 (8.08) | 974 (3.59) | |
| Age | <.0011 | <.0011 | .0022 | |
| 50–54 | 7,294 (26.9) | 739 (10.13) | 346 (4.74) | Ref |
| 55–59 | 7,238 (26.7) | 387 (5.35) | 118 (1.63) | 0.60 (0.47, 0.79) |
| 60–64 | 5,514 (20.3) | 489 (8.87) | 225 (4.08) | 0.95 (0.77, 1.16) |
| 65–69 | 4,002 (14.7) | 331 (8.27) | 164 (4.1) | 0.99 (0.78, 1.24) |
| 70–75 | 3,099 (11.4) | 247 (7.97) | 121 (3.9) | 0.94 (0.73, 1.22) |
| Sex | .421 | <.0011 | <.0012 | |
| Males | 12,662 (46.6) | 1,041 (8.22) | 357 (2.82) | Ref |
| Females | 14,485 (53.4) | 1,152 (7.95) | 617 (4.26) | 1.56 (1.33, 1.82) |
| Race/Ethnicity | <.0011 | <.0011 | .032 | |
| White | 23,028 (84.8) | 1,929 (8.38) | 892 (3.87) | Ref |
| Black | 957 (3.5) | 60 (6.27) | 13 (1.47) | 0.43 (0.23, 0.82) |
| Asian | 1,063 (3.9) | 70 (6.59) | 27 (2.54) | 0.85 (0.54, 1.35) |
| Hispanic | 1,212 (4.5) | 82 (6.77) | 30 (2.48) | 0.80 (0.52, 1.23) |
| Other/Unknown | 887 (1.0) | 52 (5.86) | 12 (1.25) | 0.58 (0.31, 1.08) |
| Prior CRC Screening | .551 | <.0011 | <.0012 | |
| Yes | 321 (1.2) | 23 (7.17) | 53 (16.51) | Ref |
| No | 26,826 (98.8) | 2,170 (8.09) | 921 (3.43) | 0.17 (0.10, 0.28) |
Chi-square P-value comparing screening rates across categories of the given characteristic separately for colonoscopy and MT-sDNA
Odds ratio and 95% confidence interval from multiple logistic regression analysis. The dependent variable for this analysis was screening method and all characteristics listed in the table were included as explanatory variables. Odds ratios>1 indicate an increased likelihood of screening with MT- sDNA. P-value represents Type 3 analysis of the effect across categories of the given characteristic
Abbreviations: CI, Confidence Interval; CRC, Colorectal Cancer; MT-sDNA, Multi-Target Stool Deoxyribonucleic Acid; OR, Odds Ratio