Table 5.
n | No. events |
Median OS |
5-years OS |
p-valuea | |
---|---|---|---|---|---|
Age | 47 | 11 | -- | -- | 0.3523 |
Primary Tumor Size | 47 | 11 | -- | -- | 0.5842 |
Gender | |||||
Female | 17 | 3 | 12.17 | 1 | 0.0209 |
Male | 30 | 8 | 10.24 | 0.78 | |
Histology | |||||
Gastrointestinal Stromal Tumor | 13 | 3 | 10.24 | 0.92 | 0.1806 |
Leiomyosarcoma | 3 | 1 | 12.17 | 1 | |
Liposarcoma | 5 | 2 | 7.52 | 1 | |
Synovial | 3 | 0 | NR | 1 | |
Chondrosarcoma | 3 | 1 | 5.96 | 1 | |
Other | 20 | 4 | NR | 0.61 | |
Original Location | |||||
Trunk | 5 | 0 | NR | NR | 0.2957 |
Abdomen/Pelvis/Retroperitoneum | 29 | 8 | 10.24 | 0.91 | |
Head & Neck | 6 | 3 | 2.78 | 0.5 | |
Extremities | 7 | 0 | NR | 1 | |
Grade | |||||
Low | 5 | 0 | NR | 1 | 0.4201 |
Intermediate/High | 36 | 10 | 10.24 | 0.85 | |
Depth | |||||
Superficial | 3 | 1 | 12.17 | 1 | 0.0534 |
Deep | 42 | 10 | 10.24 | 0.84 | |
Margins | |||||
Negative | 34 | 6 | 11.33 | 0.9 | 0.3846 |
Positive | 13 | 5 | 8.13 | 0.74 | |
Tumor PDL1 | |||||
Neg | 43 | 10 | 10.24 | 0.87 | 0.8678 |
Pos | 4 | 1 | NR | 0.75 | |
Lymphocyte PDL1 | |||||
Neg | 32 | 9 | 10.24 | 0.88 | 0.8764 |
Pos | 14 | 2 | NR | 0.76 | |
Macrophage PDL1 | |||||
Neg | 14 | 3 | 11.33 | 0.92 | 0.3326 |
Pos | 28 | 7 | 10.24 | 0.79 | |
Tumor PD1 | |||||
Neg | 37 | 8 | 11.33 | 0.85 | 0.1202 |
Pos | 10 | 3 | 8.13 | 0.71 | |
Macrophage Infiltration | |||||
No | 3 | 1 | 6.91 | 1 | 0.6489 |
Yes | 44 | 10 | 11.33 | 0.85 | |
Lymphocyte Infiltration | |||||
Yes | 47 | 11 | 10.24 | 0.86 | -- |
CD3 | |||||
0–5% | 27 | 5 | 11.33 | 0.95 | 0.0496 |
>5% | 20 | 6 | 8.13 | 0.72 | |
CD4 | |||||
0–5% | 43 | 8 | 11.33 | 0.91 | 0.0459 |
>5% | 4 | 3 | 6.51 | 0.5 | |
CD8 | |||||
0–5% | 38 | 8 | 11.33 | 0.89 | 0.091 |
>5% | 9 | 3 | 10.24 | 0.71 | |
FOXP3 | |||||
0% | 16 | 4 | 11.33 | 0.92 | 0.2598 |
1–5% | 31 | 7 | 10.24 | 0.83 | |
CD8/FOXP3 Ratio | |||||
<= 1 | 12 | 2 | 6.91 | 0.9 | 0.707 |
>1 | 12 | 4 | 10.24 | 0.79 |
Abbreviations: OS overall survival, NR not reached
: p <0.05 set as significant