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. Author manuscript; available in PMC: 2018 Jul 1.
Published in final edited form as: J Immunol. 2017 May 26;199(1):91–96. doi: 10.4049/jimmunol.1601570

Figure 2. Frequency and Phenotype analysis of βCA-specific CD4+ T cells in T1D and healthy subjects.

Figure 2

A. Detection of antigen-specific CD4+ T cells by CD154 and CD69 surface markers and expression of CD38 on memory cells in a T1D subject.

B. ICOS expression on different CD154+CD69+CD38+/- subsets in a T1D subject.

C. ICOS expression on different CD154+CD69+CD38+/- subsets in 5 T1D subjects.

D. Comparison of total βCA-specific CD4+ T cells between T1D subjects and healthy controls.

E. Comparison of naïve (CD4+CD45RO-) βCA-specific T cells between T1D subjects and healthy controls.

F. Comparison of memory (CD4+CD45RO+) βCA-specific T cells between T1D subjects and healthy controls.

G. Comparison of immune active (CD4+CD45RO+CD38+) memory βCA specific T cells between T1D subjects and healthy controls.

Data were compared using two-tail unpaired Student’s t test.