Skip to main content
. Author manuscript; available in PMC: 2017 Jul 11.
Published in final edited form as: J Mol Cell Cardiol. 2016 Apr 13;94:162–175. doi: 10.1016/j.yjmcc.2016.04.003

Figure 2.

Figure 2

Calcium and tension transients in rat cardiac muscle. A. Representative time courses of Ca2+ data used to drive the myofilament model. Frequency dependent acceleration of relaxation is clearly visible. Data are from Janssen et al. [19]. B. Model simulated tension transients were used to compute TTP, RT50 and Tdev. For these simulations, SL is fixed at 2.2 μm, temperature is 37.5 °C and metabolite concentrations are: MgATP = 8 mM; MgADP = 18 μM; Pi = 0.6 mM (representative of resting level metabolites concentrations under physiological conditions).