Table D.1.

Parameters estimated/used for simulating the CVS model

Parameter	Description	Value	Reference
Circulatory Parameters
RPV	Pulmonary vasculature resistance	19.2 mmHg sec mL−1	Fixed
RSV	Systemic vasculature resistance	117.6 mmHg sec mL−1	Fixed
RAo	Aortic resistance	1.96 mmHg sec mL−1	Arbitrarily set
CAo	Aortic compliance	0.00015 mL mmHg−1	Arbitrarily set
CSA	Systemic artery compliance	0.0035 mL mmHg−1	Fit to CVS data
CSV	Systemic vein compliance	19.33 mL mmHg−1	Fixed
CPA	Pulmonary artery compliance	2.42 mL mmHg−1	Fit to CVS data
CPV	Pulmonary vein compliance	0.009 mL mmHg−1	Fixed
τCO	Mean cardiac output time constant	5 sec	Fixed
τPA	Mean pulmonary artery time constant	30 sec	Fixed
τSA	Mean systemic artery time constant	30 sec	Fixed
TriSeg parameters
Vw,lw	LV wall volume	0.4653 mL	Determined from experiments
Vw,sw	Septal wall volume	0.2506 mL	Determined from experiments
Vw,rw	RV wall volume	0.1933 mL	Determined from experiments
$A_{\text{m,ref}}^{\text{LW}}$	LV midwall reference surface area	1.38 cm2	Fit to CVS data
$A_{\text{m,ref}}^{\text{SW}}$	Septal midwall reference surface area	0.78 cm2	Fit to CVS data
$A_{\text{m,ref}}^{\text{RW}}$	RV midwall reference surface area	2.18 cm2	Fit to CVS data
Other parameters
KSE	Stiffness of series element	5000 mmHg μm−1	See text
visc	Viscosity coefficient of myofibers	1 mmHg sec μm−1	Fixed