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Metabolite concentrations
| Parameter | Normal | Heart Failure |
|---|---|---|
| Metabolite pools (fixed parameters) | ||
| TAN, total adenine nucleotide | 8.62 mM | 4.32 mM |
| TEP, total exchangeable phosphate | 29.8 mM | 21.3 mM |
| CRTOT, total creatine pools | 36.0 mM | 22.7 mM |
| Phosphate metabolites (computed from model) | ||
| [ATP], cytoplasmic | 8.0 mM | 1.6 mM |
| [ADP], cytoplasmic | 18 μM | 4 μM |
| [Pi], cytoplasmic | 0.6 mM | 4 mM |
