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. Author manuscript; available in PMC: 2017 Jul 11.
Published in final edited form as: Sci Immunol. 2017 Mar 17;2(9):eaaj1996. doi: 10.1126/sciimmunol.aaj1996

Fig 4. LFA-1 is highly expressed on a subset of liver memory CD8+ T cells.

Fig 4

2 × 104 CD45.1+ OT-I cells were transferred to C57BL/6 mice prior to immunization with 5 × 104 P.berghei CS5M sporozoites. One, 2 and 4 weeks post-immunization organs were harvested and cells prepared for flow-cytometry analysis. (A) Representative flow cytometry plots from a single mouse at each time-point, showing the expression of CD11a (ITGAL) on CD45.1+ CD8+ OT-I T cells in the spleen, lymph nodes and liver at the indicated time-points, values indicate the percentage of cells that are CD11ahi. (B) Summary data pooled from two independent experiments showing the proportion of CD45.1+ CD8+ OT-I cells that are CD11ahi. Data were analyzed using a linear mixed model including the experiment and mouse as random effects and organ and time-point as fixed effects. Bars show means and SD.