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Comparison of three methods for radiosynthesis of [18F]DHMT.
| Method | RCY * (%) | Radiochemical Purity (%) | Specific Activity (GBq/µmol) | Synthesis Time (min) |
|---|---|---|---|---|
| Literature [9] | 42.8 | 90–100 | 13–24 | 120 |
| Manual (n = 2) | 31.6 ± 9.3 | 93.9 ± 0.6 | 426 ± 272 | ~120 |
| Automated (n = 7) | 6.9 ± 2.8 | 96.9 ± 1.7 | 155 ± 153 | ~77 |
* Decay-uncorrected RCY calculated based on the isolated product and starting [18F]fluoride.
