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. Author manuscript; available in PMC: 2018 Aug 1.
Published in final edited form as: J Cancer Res Clin Oncol. 2017 Apr 3;143(8):1421–1435. doi: 10.1007/s00432-017-2397-3

Figure 2. Kaplan-Meier Penetrance Curves.

Figure 2

A) Overall age-related penetrance for the 241 SDHB mutation carriers screened for the disease. B) Age-related penetrance in the 241 SDHB mutation carriers separated by sex. C) Overall age-related penetrance for the 241 SDHB mutation carriers screened for the disease and 103 index patients (N=344). D) Age-related penetrance in the 241 SDHB mutation carriers and 103 index patients (N=344) separated by sex. C) and D) represent penetrance estimates if analysis was not corrected for ascertainment bias.

Upper gray line represents estimated upper bound of the age-related penetrance. Lower gray line represents estimated lower bound of the age-related penetrance.