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. Author manuscript; available in PMC: 2017 Nov 29.
Published in final edited form as: Nat Med. 2017 May 29;23(7):885–889. doi: 10.1038/nm.4347

Fig 3. TZM-bl based assay (TZA) to quantify inducible replication competent HIV-1 from rCD4+ T cells.

Fig 3

a) Schematic overview of the TZA, b) Statistical comparison of the IUPM values determined by TZA or Q-VOA using a parametric unpaired T test (P=0061). c) Statistical comparison of fractional HIV-1 provirus expression (fPVE) determined by TZA or Q-VOA using a parametric ratio paired T test (P=0.0006). d) Correlation between TZA and total HIV-1 DNA in rCD4+ T cells. e) Correlation between Q-VOA and total HIV-1 DNA in rCD4+ T cells. f) Correlation between TZA and intracellular HIV-1 gag-pol mRNA+ cells/106 rCD4+ T cells. g) Correlation between TZA and Q-VOA. P values for all correlations were obtained using the Pearson test.